Posted by Laura Randle on Wednesday, June 1, 2022,
Over the last few weeks the team has been preparing and collecting slice for FFPE so that they can be H&E stained to check the structural integrity and stained for various markers to confirm the slices remain viable in culture after 2 weeks. Today we received confirmation from the pathologist that the slices are alive and have good morphology. This is a huge step forward in our project and will now be followed up with functional assays to ensure that the phenotype is maintained in culture. ...
Continue reading ...
Posted by Laura Randle on Wednesday, June 1, 2022,
I
have recently given a talk “Developing an ex-vivo tissue model of CCA using
precision cut tumour slices.” at the AMMF 2022 European
Cholangiocarcinoma conference.I joined Mr Hassan Malik and Mr Tim Gilbert as we showcased the HPB work conducted in Liverpool and the link between basic scientists like myself, the surgeons and the patients. Continue reading ...
Teaching and Learning lead, Senior Lecturer at University of Liverpool, Centre for Drug Safety Science. NC3Rs and NWCR funded researcher investigating the utilisation of precision cut tissue slices (PCTS) in the study of cholangiocarcinoma (CCA) particularly focussing on the tumour immune microenvironment.
